High-level expression of Notch1 increased the risk of metastasis in T1 stage clear cell renal cell carcinoma.

Although metastasis of clear cell renal cell carcinoma (ccRCC) is basically observed in late stage tumors, T1 stage metastasis of ccRCC can also be found with no definite molecular cause resulting inappropriate selection of surgery method and poor prognosis. Notch signaling is a conserved, widely ex...

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Bibliographic Details
Main Authors: Qing Ai, Xin Ma, Qingbo Huang, Shangwen Liu, Taoping Shi, Chao Zhang, Mingyang Zhu, Yu Zhang, Baojun Wang, Dong Ni, Hongzhao Li, Tao Zheng, Xu Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323638?pdf=render