Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.

Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.

Influenza A virus (IAV) is a seasonal pathogen with the potential to cause devastating pandemics. IAV infects multiple epithelial cell subsets in the respiratory tract, eliciting damage to the lungs. Clearance of IAV is primarily dependent on CD8+ T cells, which must balance control of the infection...

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Bibliographic Details
Main Authors: Jessica K Fiege, Ian A Stone, Rebekah E Dumm, Barbara M Waring, Brian T Fife, Judith Agudo, Brian D Brown, Nicholas S Heaton, Ryan A Langlois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008077

Internet

https://doi.org/10.1371/journal.ppat.1008077

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