Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.
Influenza A virus (IAV) is a seasonal pathogen with the potential to cause devastating pandemics. IAV infects multiple epithelial cell subsets in the respiratory tract, eliciting damage to the lungs. Clearance of IAV is primarily dependent on CD8+ T cells, which must balance control of the infection...
Main Authors: | Jessica K Fiege, Ian A Stone, Rebekah E Dumm, Barbara M Waring, Brian T Fife, Judith Agudo, Brian D Brown, Nicholas S Heaton, Ryan A Langlois |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-09-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008077 |
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