Understanding anti-tuberculosis drug efficacy: rethinking bacterial populations and how we model them

Tuberculosis still remains a global health emergency, claiming 1.5 million lives in 2013. The bacterium responsible for this disease, Mycobacterium tuberculosis (M.tb), has successfully survived within hostile host environments, adapting to immune defence mechanisms, for centuries. This has resulte...

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Bibliographic Details
Main Authors: Dimitrios Evangelopoulos, Joana Diniz da Fonseca, Simon J. Waddell
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971214017172