PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment

PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment

Shigella flexneri, the pathogen responsible for bacillary dysentery, has evolved multiple strategies to control the inflammatory response. Here, we show that Shigella subverts the subcellular trafficking of the intercellular adhesion molecule-1 (ICAM-1), a key molecule in immune cell recruitment, in...

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Bibliographic Details
Main Authors: Frédéric Boal, Andrea Puhar, Jean-Marie Xuereb, Oksana Kunduzova, Philippe J. Sansonetti, Bernard Payrastre, Hélène Tronchère
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715015351

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http://www.sciencedirect.com/science/article/pii/S2211124715015351

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