Lysosomal trafficking of TGFBIp via caveolae-mediated endocytosis.

Transforming growth factor-beta-induced protein (TGFBIp) is ubiquitously expressed in the extracellular matrix (ECM) of various tissues and cell lines. Progressive accumulation of mutant TGFBIp is directly involved in the pathogenesis of TGFBI-linked corneal dystrophy. Recent studies reported that m...

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Bibliographic Details
Main Authors: Seung-Il Choi, Yong-Sun Maeng, Tae-Im Kim, Yangsin Lee, Yong-Sun Kim, Eung Kweon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4390356?pdf=render