Resistance to Both Chemotherapy and EGFR-TKI in Small Cell Lung Cancer With EGFR 19-Del Mutation: A Case Report

Resistance to Both Chemotherapy and EGFR-TKI in Small Cell Lung Cancer With EGFR 19-Del Mutation: A Case Report

Epidermal growth factor receptor (EGFR) mutations are common in non-small cell lung cancers, but rare in small cell lung cancers (SCLCs). In previous reports, some SCLC patients with EGFR mutations could benefit from EGFR tyrosine kinase inhibitors (TKIs). In this study, we reported a case in which...

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Bibliographic Details
Main Authors: Lingfei Wang, Fangyuan Dong, Jie Su, Guanjun Du, Yang Shao, Ying Liu, Xuequn He, Liubin Bao, Wei Wang, Xin Guo, Xi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
SCLC
EGFR 19-Del
EGFR-TKI
drug resistance
PTEN mutation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01048/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01048/full

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