A New Search Method Using Association Rule Mining for Drug-Drug Interaction Based on Spontaneous Report System

A New Search Method Using Association Rule Mining for Drug-Drug Interaction Based on Spontaneous Report System

Background: Adverse events (AEs) can be caused not only by one drug but also by the interaction between two or more drugs. Therefore, clarifying whether an AE is due to a specific suspect drug or drug-drug interaction (DDI) is useful information for proper use of drugs. Whereas previous reports on t...

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Bibliographic Details
Main Authors: Yoshihiro Noguchi, Anri Ueno, Manami Otsubo, Hayato Katsuno, Ikuto Sugita, Yuta Kanematsu, Aki Yoshida, Hiroki Esaki, Tomoya Tachi, Hitomi Teramachi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
drug-drug interaction
spontaneous reporting systems
signal detection
association rule mining
apriori algorithm
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00197/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00197/full

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