2,3,7,8-Tetrachlorodibenzo-p-dioxin and up-regulation of neurofilament expression in neuronal cells: Evaluation of AhR and MAPK pathways

Dioxin exposure is reported to affect nervous system development and increase the risk of neurodegenerative diseases. Generally, dioxin exerts its neurotoxicity via aryl hydrocarbon receptor (AhR). Neurofilament (NF) light (NFL) protein is a biomarker for both neuronal differentiation and neurodegen...

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Bibliographic Details
Main Authors: Yangsheng Chen, Heidi Qunhui Xie, Rui Sha, Tuan Xu, Songyan Zhang, Hualing Fu, Yingjie Xia, Yiyun Liu, Li Xu, Bin Zhao
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412019312905