Active Components of Leptospira Outer Membrane Protein LipL32 to Toll-Like Receptor 2

Abstract Proteins belonging to the toll-like receptor (TLR) family, particularly TLR2, are the major components of innate immunity against Leptospira infection. The ligands for TLR2 harbor several conserved patterns such as lipidation molecules, leucine-rich repeat (LRR) domains, TLR2 binding motifs...

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Bibliographic Details
Main Authors: Shen-Hsing Hsu, Cheng-Chieh Hung, Ming-Yang Chang, Yi-Ching Ko, Huang-Yu Yang, Hsiang-Hao Hsu, Ya-Chung Tian, Li-Fang Chou, Rong-Long Pan, Fan-Gang Tseng, Chih-Wei Yang
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08743-y