Substrate Discrimination by ClpB and Hsp104

ClpB of E. coli and yeast Hsp104 are homologous molecular chaperones and members of the AAA+ (ATPases Associated with various cellular Activities) superfamily of ATPases. They are required for thermotolerance and function in disaggregation and reactivation of aggregated proteins that form during sev...

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Bibliographic Details
Main Authors: Danielle M. Johnston, Marika Miot, Joel R. Hoskins, Sue Wickner, Shannon M. Doyle
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00036/full