Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

Pathogenic bacteria can aggregate to form biofilms and develop tolerance to antibiotics. Here, the authors use a proteomics approach to study the development of tolerance to the antibiotic colistin in Pseudomonas aeruginosabiofilms, and show that co-treatment with a second compound kills the toleran...

Full description

Bibliographic Details
Main Authors: Song Lin Chua, Joey Kuok Hoong Yam, Piliang Hao, Sunil S. Adav, May Margarette Salido, Yang Liu, Michael Givskov, Siu Kwan Sze, Tim Tolker-Nielsen, Liang Yang
Format: Article
Language:English
Published: Nature Publishing Group 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10750