A co-ultramicronized palmitoylethanolamide/luteolin composite mitigates clinical score and disease-relevant molecular markers in a mouse model of experimental autoimmune encephalomyelitis

A co-ultramicronized palmitoylethanolamide/luteolin composite mitigates clinical score and disease-relevant molecular markers in a mouse model of experimental autoimmune encephalomyelitis

Abstract Background Persistent and/or recurrent inflammatory processes are the main factor leading to multiple sclerosis (MS) lesions. The composite ultramicronized palmitoylethanolamide, an endogenous N-acylethanolamine, combined with the flavonoid luteolin, PEALut, have been found to exert neuropr...

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Bibliographic Details
Main Authors: Gabriella Contarini, Davide Franceschini, Laura Facci, Massimo Barbierato, Pietro Giusti, Morena Zusso
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
EAE, Acute phase response
PEALut
Online Access:http://link.springer.com/article/10.1186/s12974-019-1514-4

Internet

http://link.springer.com/article/10.1186/s12974-019-1514-4

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