BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression

Summary BUBR1 is a mitotic phosphoprotein essential for the maintenance of chromosome stability by promoting chromosome congression and proper kinetochore–microtubule (K-fiber) attachment, but the underlying mechanism(s) has remained elusive. Here we identify BUBR1 as a binding partner of the B56 fa...

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Bibliographic Details
Main Authors: Peng Xu, Elizabeth A. Raetz, Mayumi Kitagawa, David M. Virshup, Sang Hyun Lee
Format: Article
Language:English
Published: The Company of Biologists 2013-03-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/5/479