Fusogenicity of the Ghana Virus (<i>Henipavirus</i>: <i>Ghanaian bat henipavirus</i>) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein

Fusogenicity of the Ghana Virus (<i>Henipavirus</i>: <i>Ghanaian bat henipavirus</i>) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein

The Ghana virus (GhV) is phylogenetically related to the zoonotic henipaviruses Nipah (NiV) and Hendra virus. Although GhV uses the highly conserved receptor ephrin-B2, the fusogenicity is restricted to cell lines of bat origin. Furthermore, the surface expression of the GhV attachment glycoprotein...

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Bibliographic Details
Main Authors: Kathleen Voigt, Markus Hoffmann, Jan Felix Drexler, Marcel Alexander Müller, Christian Drosten, Georg Herrler, Nadine Krüger
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Viruses
Subjects:
Ghana virus
attachment glycoprotein
fusion
intracellular retention
Online Access:https://www.mdpi.com/1999-4915/11/9/800

Internet

https://www.mdpi.com/1999-4915/11/9/800

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