Use of Favipiravir to Treat Lassa Virus Infection in Macaques

Use of Favipiravir to Treat Lassa Virus Infection in Macaques

Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus–viremic macaques and found that 300 mg/kg daily for...

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Bibliographic Details
Main Authors: Kyle Rosenke, Heinz Feldmann, Jonna B. Westover, Patrick William Hanley, Cynthia Martellaro, Friederike Feldmann, Greg Saturday, Jamie Lovaglio, Dana P. Scott, Yousuke Furuta, Takashi Komeno, Brian B. Gowen, David Safronetz
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2018-09-01
Series:Emerging Infectious Diseases
Subjects:
Lassa virus
antiviral
favipiravir
treatment
viruses
macaques
Online Access:https://wwwnc.cdc.gov/eid/article/24/9/18-0233_article

Internet

https://wwwnc.cdc.gov/eid/article/24/9/18-0233_article

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