Morphologic evaluation of the effect of denosumab on giant cell tumors of bone and a new grading scheme

Morphologic evaluation of the effect of denosumab on giant cell tumors of bone and a new grading scheme

Giant cell tumor (GCT) is a rare, usually benign but locally aggressive neoplasm. Recent studies suggest new approaches in light of the elucidation of molecular pathways in bone. The osteolytic nature of GCT is caused by the receptor for activating nuclear factor-kB ligand (RANKL) associated osteocl...

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Bibliographic Details
Main Authors: Kivilcim Eren Erdogan, Mehmet Ali DevecI, Semra Paydas, GulfIlIz Gonlusen
Format: Article
Language:English
Published: Termedia Publishing House 2017-02-01
Series:Polish Journal of Pathology
Subjects:
denosumab
giant cell tumor of bone
pathology
grading
treatment
RANKL
Online Access:https://www.termedia.pl/Morphologic-evaluation-of-the-effect-of-denosumab-on-giant-cell-tumors-of-bone-and-a-new-grading-scheme,55,29482,1,1.html

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https://www.termedia.pl/Morphologic-evaluation-of-the-effect-of-denosumab-on-giant-cell-tumors-of-bone-and-a-new-grading-scheme,55,29482,1,1.html

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