Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells1

Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells1

High arachidonic acid (20:4n-6) and low n-3 PUFA levels impair the capacity of cultured human bone marrow mesenchymal stromal cells (hBMSCs) to modulate immune functions. The capacity of the hBMSCs to modify PUFA structures was found to be limited. Therefore, different PUFA supplements given to the...

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Bibliographic Details
Main Authors: Feven Tigistu-Sahle, Milla Lampinen, Lotta Kilpinen, Minna Holopainen, Petri Lehenkari, Saara Laitinen, Reijo Käkelä
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Lipid Research
Subjects:
arachidonic acid
docosahexaenoic acid
eicosapentaenoic acid
glycerophospholipid
immunomodulation
lipid signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314395

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http://www.sciencedirect.com/science/article/pii/S0022227520314395

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