Protein Engineering of a Pyridoxal-5′-Phosphate-Dependent <span style="font-variant: small-caps">l</span>-Aspartate-α-Decarboxylase from <i>Tribolium castaneum</i> for β-Alanine Production
In the present study, a pyridoxal-5′-phosphate (PLP)-dependent L-aspartate-α-decarboxylase from <i>Tribolium castaneum</i> (TcPanD) was selected for protein engineering to efficiently produce β-alanine. A mutant <i>Tc</i>PanD-R98H/K305S with a 2.45...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/6/1280 |