BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge.

BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge.

Monkeypox virus (MPXV) is the etiological agent of human (MPX). It is an emerging orthopoxvirus zoonosis in the tropical rain forest of Africa and is endemic in the Congo-basin and sporadic in West Africa; it remains a tropical neglected disease of persons in impoverished rural areas. Interaction of...

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Main Authors: Valentina Franceschi, Scott Parker, Sarah Jacca, Ryan W Crump, Konstantin Doronin, Edguardo Hembrador, Daniela Pompilio, Giulia Tebaldi, Ryan D Estep, Scott W Wong, Mark R Buller, Gaetano Donofrio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4473039?pdf=render

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http://europepmc.org/articles/PMC4473039?pdf=render

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