Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies

Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies

Abstract Background Extracellular acidosis is a condition found within the tumor microenvironment due to inadequate blood perfusion, hypoxia, and altered tumor cell metabolism. Acidosis has pleiotropic effects on malignant progression; therefore it is essential to understand how acidosis exerts its...

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Bibliographic Details
Main Authors: Calvin R. Justus, Edward J. Sanderlin, Lixue Dong, Tianai Sun, Jen-Tsan Chi, Kvin Lertpiriyapong, Li V. Yang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Translational Medicine
Subjects:
TDAG8
GPR65
Acidosis
Tumor microenvironment
Hematological malignancies
Online Access:http://link.springer.com/article/10.1186/s12967-017-1305-6

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http://link.springer.com/article/10.1186/s12967-017-1305-6

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