Expression of active human sialyltransferase ST6GalNAcI in <it>Escherichia coli</it>

<p>Abstract</p> <p>Background</p> <p>The presence of terminal, surface-exposed sialic acid moieties can greatly enhance the <it>in vivo </it>half-life of glycosylated biopharmaceuticals and improve their therapeutic efficacy. Complete and homogeneous sialyla...

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Bibliographic Details
Main Authors: Schwartz Marc F, DeFrees Shawn, Carroll Sean, Skretas Georgios, Johnson Karl F, Georgiou George
Format: Article
Language:English
Published: BMC 2009-09-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/8/1/50