Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia

Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia

Abstract The epidermal growth factor receptor (EGFR) inhibitor erlotinib has been shown to induce complete remission of acute myeloid leukemia (AML) in two patients with concurrent lung cancer and raised attention for a role of EGFR in AML whereas a recent phase II clinical study with gefitinib in A...

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Bibliographic Details
Main Authors: Hasan Mahmud, Steven M. Kornblau, Arja ter Elst, Frank J. G. Scherpen, Yi Hua Qiu, Kevin R. Coombes, Eveline S. J. M. de Bont
Format: Article
Language:English
Published: BMC 2016-08-01
Series:Journal of Hematology & Oncology
Subjects:
EGFR
AML
RPPA
Kinome
Leukemia
Online Access:http://link.springer.com/article/10.1186/s13045-016-0294-x

Internet

http://link.springer.com/article/10.1186/s13045-016-0294-x

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