Antimicrobial Activity of Nitrogen-Containing 5-Alpha-androstane Derivatives: In Silico and Experimental Studies

Antimicrobial Activity of Nitrogen-Containing 5-Alpha-androstane Derivatives: In Silico and Experimental Studies

We evaluated the antimicrobial activity of thirty-one nitrogen-containing 5-alpha-androstane derivatives in silico using computer program PASS (Prediction of Activity Spectra for Substances) and freely available PASS-based web applications (www.way2drug.com). Antibacterial activity was predicted for...

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Bibliographic Details
Main Authors: Lela Amiranashvili, Nanuli Nadaraia, Maia Merlani, Charalampos Kamoutsis, Anthi Petrou, Athina Geronikaki, Pavel Pogodin, Dmitry Druzhilovskiy, Vladimir Poroikov, Ana Ciric, Jasmina Glamočlija, Marina Sokovic
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Antibiotics
Subjects:
antibacterial activity
antifungal activity
potency against the resistant strains
PASS
GUSAR
CLC-Pred
Online Access:https://www.mdpi.com/2079-6382/9/5/224

Internet

https://www.mdpi.com/2079-6382/9/5/224

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