The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress.

The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress.

<h4>Background</h4>Hypertonicity can perturb cellular functions, induce DNA damage-like responses and inhibit proliferation. The transcription factor NFAT5 induces osmoprotective gene products that allow cells to adapt to sustained hypertonic conditions. Although it is known that NFAT5-d...

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Bibliographic Details
Main Authors: Katherine Drews-Elger, M Carmen Ortells, Anjana Rao, Cristina López-Rodriguez, Jose Aramburu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19381288/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19381288/?tool=EBI

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