DNA methylation and gene expression of TXNIP in adult offspring of women with diabetes in pregnancy.

DNA methylation and gene expression of TXNIP in adult offspring of women with diabetes in pregnancy.

Fetal exposure to maternal diabetes increases the risk of type 2 diabetes (T2DM), possibly mediated by epigenetic mechanisms. Low blood TXNIP DNA methylation has been associated with elevated glucose levels and risk of T2DM, and increased skeletal muscle TXNIP gene expression was reported in subject...

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Bibliographic Details
Main Authors: Azadeh Houshmand-Oeregaard, Line Hjort, Louise Kelstrup, Ninna S Hansen, Christa Broholm, Linn Gillberg, Tine D Clausen, Elisabeth R Mathiesen, Peter Damm, Allan Vaag
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5659766?pdf=render

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http://europepmc.org/articles/PMC5659766?pdf=render

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