Ubiquitous neurocognitive dysfunction in familial adenomatous polyposis: proof-of-concept of the role of APC protein in neurocognitive function

Ubiquitous neurocognitive dysfunction in familial adenomatous polyposis: proof-of-concept of the role of APC protein in neurocognitive function

Abstract Background Familial adenomatous polyposis (FAP) is an autosomal dominant disorder caused by germline mutations in the APC gene. Patients with FAP have multiple extraintestinal manifestations that follow a genotype-phenotype pattern; however, few data exist characterizing their cognitive abi...

Full description

Bibliographic Details
Main Authors: Marcia Roxana Cruz-Correa, Ana Cecilia Sala, Beatriz Cintrón, Jessica Hernández, Myrta Olivera, Adrian Cora, Constance M. Moore, Carlos A. Luciano, Marievelisse Soto-Salgado, Francis M. Giardiello, Stephen R. Hooper
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Familial adenomatous polyposis
Neurocognition
Hispanics
FAP
Online Access:http://link.springer.com/article/10.1186/s13053-020-0135-3

Internet

http://link.springer.com/article/10.1186/s13053-020-0135-3

Similar Items