Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies.

<h4>Background</h4>Severe falciparum malaria is a medical emergency characterised by potentially lethal vital organ dysfunction. Patient fatality rates even with parenteral artesunate treatment remain high. Despite considerable research into adjuvant therapies targeting organ and tissue...

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Bibliographic Details
Main Authors: Stije J Leopold, James A Watson, Atthanee Jeeyapant, Julie A Simpson, Nguyen H Phu, Tran T Hien, Nicholas P J Day, Arjen M Dondorp, Nicholas J White
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002858