Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19

Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19

Abstract An excessive immune response known as cytokine storm is the hallmark of severe COVID-19. The cause of this cytokine rampage is yet not known. Based on recent epidemiological evidence, we hypothesized that CD80/86 signaling is essential for this hyperinflammation, and that blocking this proi...

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Bibliographic Details
Main Authors: Antonio Julià, Irene Bonafonte-Pardàs, Antonio Gómez, María López-Lasanta, Mireia López-Corbeto, Sergio H. Martínez-Mateu, Jordi Lladós, Iván Rodríguez-Nunez, Richard M. Myers, Sara Marsal
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90797-0

Internet

https://doi.org/10.1038/s41598-021-90797-0

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