Alzheimer's disease risk modifier genes do not affect tau aggregate uptake, seeding or maintenance in cell models
Alzheimer's disease (AD) afflicts millions of people worldwide and is caused by accumulated amyloid beta and tau pathology. Progression of tau pathology in AD may utilize prion mechanisms of propagation in which pathological tau aggregates released from one cell are taken up by neighboring or c...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-09-01
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Series: | FEBS Open Bio |
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Online Access: | https://doi.org/10.1002/2211-5463.12928 |