How much allopurinol does it take to get to target urate? Comparison of actual dose with creatinine clearance-based dose
Abstract Objective Allopurinol dosing has frequently been limited based on creatinine clearance (CrCL), resulting in failure to achieve target serum urate (SU). The aim of this analysis was to determine how many milligrams of allopurinol above the recommended CrCL-based dose (R+) are required to ach...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | Arthritis Research & Therapy |
Online Access: | http://link.springer.com/article/10.1186/s13075-018-1755-0 |