Antimicrobial and antibiofilm activity of the EeCentrocin 1 derived peptide EC1-17KV via membrane disruption

Antimicrobial and antibiofilm activity of the EeCentrocin 1 derived peptide EC1-17KV via membrane disruption

ABSTRACT: Background: The antibiotic resistance and biofilm formation of pathogenic microbes exacerbate the difficulties of anti-infection therapy in the clinic. The structural modification of antimicrobial peptides (AMP) is an effective strategy to develop novel anti-infective agents. Method: Seve...

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Bibliographic Details
Main Authors: Lingman Ma, Xinyue Ye, Pengbo Sun, Pengfei Xu, Liping Wang, Zixiang Liu, Xiaowei Huang, Zhaoshi Bai, Changlin Zhou
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:EBioMedicine
Subjects:
Antibiotic resistance
AMP structural modification
EC1-17KV
Antimicrobial activity
Membrane destruction
Antibiofilm effect
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642030150X

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http://www.sciencedirect.com/science/article/pii/S235239642030150X

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