Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide–Glycyrrhetinic-Acid-Based Derivatives

Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide–Glycyrrhetinic-Acid-Based Derivatives

Glycyrrhetinic acid (GA) is one of many interesting pentacyclic triterpenoids showing significant anticancer activity by triggering apoptosis in tumor cell lines. This study deals with the design and synthesis of new glycyrrhetinic acid (GA)–amino acid peptides and peptide ester derivatives. The str...

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Bibliographic Details
Main Authors: Gaber O. Moustafa, Ahmed Shalaby, Ahmed M. Naglah, Marwa M. Mounier, Heba El-Sayed, Manal M. Anwar, Eman S. Nossier
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
glycyrrhetinic acid
peptide derivatives
anticancer potentiality
apoptotic markers
antimicrobial activity
molecular docking studies
Online Access:https://www.mdpi.com/1420-3049/26/15/4573

Internet

https://www.mdpi.com/1420-3049/26/15/4573

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