The TT genotype of the STAT4 rs7574865 polymorphism is associated with high disease activity and disability in patients with early arthritis.

The TT genotype of the STAT4 rs7574865 polymorphism is associated with high disease activity and disability in patients with early arthritis.

BACKGROUND: The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis. In the present study, we investigated the effects of these genetic vari...

Full description

Bibliographic Details
Main Authors: Amalia Lamana, Alejandro Balsa, Blanca Rueda, Ana M Ortiz, Laura Nuño, Maria Eugenia Miranda-Carus, Maria F Gonzalez-Escribano, Miguel A Lopez-Nevot, Dora Pascual-Salcedo, Javier Martin, Isidoro González-Álvaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427144?pdf=render

Internet

http://europepmc.org/articles/PMC3427144?pdf=render

Similar Items