Twin arginine translocation, ammonia incorporation, and polyamine biosynthesis are crucial for Proteus mirabilis fitness during bloodstream infection.

Twin arginine translocation, ammonia incorporation, and polyamine biosynthesis are crucial for Proteus mirabilis fitness during bloodstream infection.

The Gram-negative bacterium Proteus mirabilis is a common cause of catheter-associated urinary tract infections (CAUTI), which can progress to secondary bacteremia. While numerous studies have investigated experimental infection with P. mirabilis in the urinary tract, little is known about pathogene...

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Bibliographic Details
Main Authors: Chelsie E Armbruster, Valerie S Forsyth, Alexandra O Johnson, Sara N Smith, Ashley N White, Aimee L Brauer, Brian S Learman, Lili Zhao, Weisheng Wu, Mark T Anderson, Michael A Bachman, Harry L T Mobley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007653

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https://doi.org/10.1371/journal.ppat.1007653

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