Somatic Mutations of the PPP2R1B Candidate Tumor Suppressor Gene at Chromosome 11q23 are Infrequent in Ovarian Carcinomas

Previous studies have demonstrated frequent allelic losses of distal chromosome 11q in ovarian carcinomas. The tumor suppressor gene(s) presumably targeted by these losses have not yet been identified. PPP2R1B is a candidate tumor suppressor gene at 11q23 that has recently been shown to be mutated...

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Bibliographic Details
Main Authors: Rong Wu, Denise C. Connolly, Xiaodan Ren, Eric R. Fearon, Kathleen R. Cho
Format: Article
Language:English
Published: Elsevier 1999-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800219