Orphan nuclear receptor Nurr1 promotes Helicobacter pylori-associated gastric carcinogenesis by directly enhancing CDK4 expression

Background: Abnormal expression of the orphan nuclear receptor Nurr1 is a critical factor in the etiology of multiple cancers. However, its potential role in gastric cancer (GC) remains elusive. In this study, we have demonstrated that the expression of Nurr1 was elevated and had an oncogenic functi...

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Bibliographic Details
Main Authors: Wenjing Shang, Xiuming Liang, Shuyan Li, Tongyu Li, Lixin Zheng, Wei Shao, Yue Wang, Fen Liu, Lin Ma, Jihui Jia
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300475