Magnesium and Calcium Homeostasis Depend on KCTD1 Function in the Distal Nephron

Summary: Magnesium (Mg2+) homeostasis depends on active transcellular Mg2+ reuptake from urine in distal convoluted tubules (DCTs) via the Mg2+ channel TRPM6, whose activity has been proposed to be regulated by EGF. Calcium (Ca2+) homeostasis depends on paracellular reabsorption in the thick ascendi...

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Bibliographic Details
Main Author: Alexander G. Marneros
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720316053