Magnesium and Calcium Homeostasis Depend on KCTD1 Function in the Distal Nephron
Summary: Magnesium (Mg2+) homeostasis depends on active transcellular Mg2+ reuptake from urine in distal convoluted tubules (DCTs) via the Mg2+ channel TRPM6, whose activity has been proposed to be regulated by EGF. Calcium (Ca2+) homeostasis depends on paracellular reabsorption in the thick ascendi...
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Format: | Article |
Language: | English |
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Elsevier
2021-01-01
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Series: | Cell Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124720316053 |