Known mutations of apoB account for only a small minority of hypobetalipoproteinemia

Known mutations of apoB account for only a small minority of hypobetalipoproteinemia

Low LDL cholesterol and apoB levels in plasma cosegregate with mutations of apoB in some kindreds with familial hypobetalipoproteinemia. Approximately 35 apoB mutations, many specifying apoB truncations, have been described. Based on the centile nomenclature where the full-length nature apoB consist...

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Bibliographic Details
Main Authors: Jingshi Wu, Jeongho Kim, Qun Li, Pui-Yan Kwok, Thomas G. Cole, Baldassare Cefalu, Maurizio Averna, Gustav Schonfeld
Format: Article
Language:English
Published: Elsevier 1999-05-01
Series:Journal of Lipid Research
Subjects:
familial hypobetalipoproteinemia
low cholesterol
apoB gene mutation
apoB truncation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520321313

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http://www.sciencedirect.com/science/article/pii/S0022227520321313

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