iPromoter-5mC: A Novel Fusion Decision Predictor for the Identification of 5-Methylcytosine Sites in Genome-Wide DNA Promoters

The hypomethylation of the whole cancer genome and the hypermethylation of the promoter of specific tumor suppressor genes are the important reasons for the rapid proliferation of cancer cells. Therefore, obtaining the distribution of 5-methylcytosine (5mC) in promoters is a key step to further unde...

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Bibliographic Details
Main Authors: Lei Zhang, Xuan Xiao, Zhao-Chun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00614/full