Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis

Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis

Despite the well-established role of heterochromatin in protecting chromosomal integrity during meiosis and mitosis, the contribution and extent of heterochromatic histone posttranslational modifications (PTMs) remain poorly defined. Here, we gained novel functional insight about heterochromatic PTM...

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Bibliographic Details
Main Authors: Romeo Papazyan, Ekaterina Voronina, Jessica R Chapman, Teresa R Luperchio, Tonya M Gilbert, Elizabeth Meier, Samuel G Mackintosh, Jeffrey Shabanowitz, Alan J Tackett, Karen L Reddy, Robert S Coyne, Donald F Hunt, Yifan Liu, Sean D Taverna
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
Tetrahymena thermophila
histone
chromatin
methylation
meiosis
DNA damage
Online Access:https://elifesciences.org/articles/02996

Internet

https://elifesciences.org/articles/02996

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