Generation of 5 induced pluripotent stem cell lines, LUMCi007-A and B and LUMCi008-A, B and C, from 2 patients with Huntington disease

Huntington disease (HD) is an autosomal dominant, neurodegenerative disease caused by a CAG repeat expansion within the coding sequence of the HTT gene, resulting in a highly toxic protein with an expanded polyglutamine stretch that forms typical protein aggregates throughout the brain. We generated...

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Bibliographic Details
Main Authors: Linda M. van der Graaf, Sarah L. Gardiner, Merve Tok, Tom Brands, Merel W. Boogaard, Barry A. Pepers, Bert Eussen, Annelies de Klein, N. Ahmad Aziz, Christian Freund, Ronald A.M. Buijsen, Willeke M.C. van Roon-Mom
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S187350611930128X