Branched-chain amino acids ameliorate fibrosis and suppress tumor growth in a rat model of hepatocellular carcinoma with liver cirrhosis.

PURPOSE: Recent studies have revealed that branched-chain amino acids (BCAA) reduce the development of hepatocellular carcinoma (HCC) in patients with obesity and hepatitis C virus infection by improving insulin resistance (IR). The aim of this study was to examine the anti-cancer and anti-fibrotic...

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Bibliographic Details
Main Authors: Jung Hoon Cha, Si Hyun Bae, Hye Lim Kim, Na Ri Park, Eun Suk Choi, Eun Sun Jung, Jong Young Choi, Seung Kew Yoon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3815299?pdf=render