Exposure to a northern contaminant mixture (NCM) alters hepatic energy and lipid metabolism exacerbating hepatic steatosis in obese JCR rats.

Exposure to a northern contaminant mixture (NCM) alters hepatic energy and lipid metabolism exacerbating hepatic steatosis in obese JCR rats.

Non-alcoholic fatty liver disease (NAFLD), defined by the American Liver Society as the buildup of extra fat in liver cells that is not caused by alcohol, is the most common liver disease in North America. Obesity and type 2 diabetes are viewed as the major causes of NAFLD. Environmental contaminant...

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Bibliographic Details
Main Authors: Ryan J Mailloux, Maria Florian, Qixuan Chen, Jin Yan, Ivan Petrov, Melanie C Coughlan, Mahemuti Laziyan, Don Caldwell, Michelle Lalande, Dominique Patry, Claude Gagnon, Kurtis Sarafin, Jocelyn Truong, Hing Man Chan, Nimal Ratnayake, Nanqin Li, William G Willmore, Xiaolei Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0106832

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https://doi.org/10.1371/journal.pone.0106832

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