High Specificity of Quantitative Methylation-Specific PCR Analysis for MGMT Promoter Hypermethylation Detection in Gliomas

High Specificity of Quantitative Methylation-Specific PCR Analysis for MGMT Promoter Hypermethylation Detection in Gliomas

Normal brain tissue from 28 individuals and 50 glioma samples were analyzed by real-time Quantitative Methylation-Specific PCR (QMSP). Data from this analysis were compared with results obtained on the same samples by MSP. QMSP analysis demonstrated a statistically significant difference in both met...

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Main Authors: Paola Parrella, Antonella la Torre, Massimiliano Copetti, Vanna M. Valori, Raffaela Barbano, Angelo Notarangelo, Michele Bisceglia, Antonietta Pia Gallo, Teresa Balsamo, Maria Luana Poeta, Massimo Carella, Domenico Catapano, Salvatore Parisi, Bruno Dallapiccola, Evaristo Maiello, Vincenzo D'Angelo, Vito Michele Fazio
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2009/531692

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http://dx.doi.org/10.1155/2009/531692

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