Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS.

Despite tremendous progress in our understanding of human immunodeficiency virus (HIV) natural history and advances in HIV treatment, there is neither an approved vaccine nor a cure for infection. Here, we describe the development and characterization of a novel replicating vaccine vector utilizing...

Full description

Bibliographic Details
Main Authors: Jesse D Deere, W L William Chang, Luis D Castillo, Kim A Schmidt, Hung T Kieu, Nicholas Renzette, Timothy Kowalik, Stephen W Barthold, Barbara L Shacklett, Peter A Barry, Ellen E Sparger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4868283?pdf=render