Physical Absorption of Folic Acid and Chitosan on Dihydroartemisinin-Loaded Poly-Lactic-Co-Glycolic Acid Nanoparticles via Electrostatic Interaction for Their Enhanced Uptake and Anticancer Effect

In this study, dihydroartemisinin (DAR), an anticancer agent with low toxicity, was loaded into poly-lactic-co-glycolic acid (PLGA) nanoparticles. The obtained PLGA cores were then coated with chitosan (CS) and/or folic acid (FA) by electrostatic interactions to enhance their anticancer and cellular...

Full description

Bibliographic Details
Main Authors: Chien Ngoc Nguyen, Bao Ngoc Tran, Hoa Nguyen Thi, Phong Pham Huu, Huong Nguyen Thi
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2019/6808530