New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins

New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins

The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA. Inosine can have a profound effect on the RNAs that are edited, not only changing the base-pairing properties, but can also result in recoding, as inosine...

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Bibliographic Details
Main Authors: Niamh Mannion, Fabiana Arieti, Angela Gallo, Liam P. Keegan, Mary A. O'Connell
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Biomolecules
Subjects:
ADAR
RNA editing
Alu elements
dsRBDs
deaminase domain
cancer
Online Access:http://www.mdpi.com/2218-273X/5/4/2338

Internet

http://www.mdpi.com/2218-273X/5/4/2338

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