Heterologous expression, purification and function of the extracellular domain of human RANK

Heterologous expression, purification and function of the extracellular domain of human RANK

Abstract Background Receptor activator of NF-κB ligand (RANKL)/RANK signaling essentially functions within the skeletal system, particularly participating in osteoclastogenesis and bone resorption. In addition, this signaling pathway has also been shown to influence tumor progression as well as the...

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Bibliographic Details
Main Authors: Yilei Wei, Yu Zhan, Pengfei Chen, Zhi Liu, Haohao Zhang, Dandan Liu, Jie Zhang, Min Yu, Wei Mo, Jun Zhang, Xiaoren Zhang
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Biotechnology
Subjects:
RANK
Pichia pastoris
Protein purification
Bone diseases
Colorectal cancer
Online Access:http://link.springer.com/article/10.1186/s12896-017-0405-y

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http://link.springer.com/article/10.1186/s12896-017-0405-y

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