The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration

The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration

The Wnt pathway has been shown to regulate bone homeostasis and to influence some bone disease states. We utilized a zebrafish model system to study the effects of a synthetic, orally bioavailable glycogen synthase kinase-3β (GSK3β) inhibitor LSN 2105786, which activates Wnt signal...

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Bibliographic Details
Main Authors: Swapnalee Sarmah, Courtney Curtis, Jennifer Mahin, Mark Farrell, Thomas A. Engler, Manuel V. Sanchez-Felix, Masahiko Sato, Yanfai Linda Ma, Shaoyou Chu, James A. Marrs
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biomedicines
Subjects:
zebrafish
glycogen synthase kinase-3β
bone healing
regeneration
caudal fin
Online Access:https://www.mdpi.com/2227-9059/7/2/30

Internet

https://www.mdpi.com/2227-9059/7/2/30

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